ANATOMY

Detailed explanation-1: -When the urinary bladder fills with urine, the bladder wall stretches to accommodate the increased volume. In the distended bladder, the urothelium reorganizes into two or three layers without any structural damage. Due to this transitional ability of the urothelium, it is also known as the transitional epithelium.

Detailed explanation-2: -The urothelium is the inner lining of the bladder. It is made up of urothelial cells (also called transitional cells). The urothelium is also called the transitional epithelium. The lamina propria (also called the submucosa) is a thin layer of connective tissue that surrounds the urothelium.

Detailed explanation-3: -The transitional epithelium of the urinary tract is lined by a layer of glycosaminoglycans (GAGs) that function to prevent microbial and crystal adherence to the bladder epithelium and minimize the movement of urine solutes and proteins through the bladder epithelium.