ANATOMY

Detailed explanation-1: -Uremia is a buildup of toxins in your blood. It occurs when the kidneys stop filtering toxins out through your urine. Uremia is often a sign of end-stage renal (kidney) disease. Treatments include medication, dialysis and kidney transplant surgery.

Detailed explanation-2: -Uremia occurs when your kidneys become damaged. The toxins, or bodily waste, that your kidneys normally send out in your urine end up in your bloodstream instead. These toxins are known as creatinine and urea. Uremia is a serious condition and, if untreated, can be life-threatening.

Detailed explanation-3: -Uremia can lead to kidney failure when left untreated. Someone with uremia may have seizures, loss of consciousness, heart attacks, and other life-threatening symptoms. Some will need a kidney transplant. Kidney failure may also damage other organs, so untreated uremia can result in liver or heart failure.

Detailed explanation-4: -The literal meaning of uremia is “urine in the blood, ” and the condition develops most commonly in the setting of chronic and end-stage renal disease (ESRD), but may also occur as a result of acute kidney injury.

Detailed explanation-5: -Removing waste from the blood Two examples of the most common waste products are creatinine and urea. Creatinine is a waste product formed as a result of normal muscle activity. Urea is the by-product of protein and amino acid breakdown.