ANATOMY

Detailed explanation-1: -The environment of the medulla has a higher osmolarity than the inside of the nephron. You know what that means-osmosis time! Water travels from inside the nephron tubes, through a semipermeable membrane, out into the medulla. Eventually, concentrated urine is left in the nephron.

Detailed explanation-2: -The Loop of Henle Filtered fluid first passes through the descending limb. Here, water flows out of the tubule into the surrounding tissue, as the walls of the nephron are permeable to water in this part of the structure.

Detailed explanation-3: -Water reabsorption is a passive process: water is reabsorbed by osmosis. In most of the nephron there is unregulated isosmotic reabsorption of water and solute, in other words, water reabsorption is coupled to solute reabsorption.

Detailed explanation-4: -In summary, the loop of Henle is surrounded by tissue fluid which has a high concentration of ions in it. This causes water to move out of the descending limb by osmosis. This produces a more concentrated filtrate because of this, ions move out of the loop in the thin ascending limb.

Detailed explanation-5: -Each of the nephrons contain a filter called the glomerulus (pronounced: gluh-MER-yuh-lus). The fluid that is filtered out from the blood then travels down a tiny tube-like structure called a tubule (pronounced: TOO-byool). The tubule adjusts the level of salts, water, and wastes that will leave the body in the urine.