ANATOMY

Detailed explanation-1: -Nausea and vomiting, muscle cramps, loss of appetite, swelling via feet and ankles, dry, itchy skin, shortness of breath, trouble sleeping, urinating either too much or too little.

Detailed explanation-2: -Symptoms and Signs of CKD Lassitude, fatigue, anorexia, and decreased mental acuity often are the earliest manifestations of uremia.

Detailed explanation-3: -Urine Tests One of the earliest signs of kidney disease is when protein leaks into your urine (called proteinuria). To check for protein in your urine, a doctor will order a urine test.

Detailed explanation-4: -Patients presenting with uremia typically complain of nausea, vomiting, fatigue, anorexia, weight loss, muscle cramps, pruritus, or changes in mental status. The clinical presentation of uremia can be explained by the metabolic disturbances associated with the condition.