ANATOMY

Detailed explanation-1: -When the nephrons don’t get enough blood they are severely damaged. As a result, the blood can’t pass through the kidneys and the nephrons can’t filter wastes from the blood, or perform their other functions.

Detailed explanation-2: -If nephrons are damaged, they stop working. For a while, healthy nephrons can take on the extra work. But if the damage continues, more and more nephrons shut down. After a certain point, the nephrons that are left cannot filter your blood well enough to keep you healthy.

Detailed explanation-3: -When your kidneys lose their filtering ability, dangerous levels of wastes may accumulate, and your blood’s chemical makeup may get out of balance. Acute kidney failure-also called acute renal failure or acute kidney injury-develops rapidly, usually in less than a few days.

Detailed explanation-4: -High blood pressure and diabetes are the two most common causes of kidney failure. They can also become damaged from physical injury, diseases, or other disorders.

Detailed explanation-5: -Nephrotic syndrome is a kidney disorder that causes your body to pass too much protein in your urine. Nephrotic syndrome is usually caused by damage to the clusters of small blood vessels in your kidneys that filter waste and excess water from your blood.