ANATOMY

Detailed explanation-1: -The descending limb of the loop of Henle is permeable to water. Water diffuses into the hyperosmolar medullary interstitium. The osmolarity can reach a maximum of 1200 mOsm/L at the tip of the medullary interstitium in antidiuresis. The ascending limb (where loop diuretics work) is impermeable to water.

Detailed explanation-2: -The descending portion of the loop of Henle is extremely permeable to water and is less permeable to ions, therefore water is easily reabsorbed here and solutes are not readily reabsorbed.

Detailed explanation-3: -2) Descending limb of loop of Henle is permeable to water but is impermeable to electrolytes.

Detailed explanation-4: -The thin descendant limb of the Henle loop is highly permeable to water but less permeable to urea and ions. Because water is reabsorbed together with ions via the gradient time system to maintain the fluid’s osmolarity in the PCT, the fluid is isotonic.

Detailed explanation-5: -The primary site of sodium reabsorption in the Loop of Henle is the thick ascending limb (TAL). The TAL is impermeable to water.