ANATOMY
CHEST AND CARDIOVASCULAR
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Which of the following is true about blood type O?
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It contains antigen A only.
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It contains antigen B only.
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It contains both antigen A and antigen B.
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It doesn’t contain antigen A or antigen B.
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Explanation:
Detailed explanation-1: -ABO antigens are added to N-linked oligosaccharide chains on the VWF subunit. Thus patients with the type O blood group genotype lack the functional glycosyltransferase that adds N-acetylgalactosamine and D-galactose to the H antigen on VWF in blood group A and B subjects, respectively.
Detailed explanation-2: -Blood group O has no antigens, but has both anti-A and anti-B antibodies in the plasma, as well as some special “anti-A, B” antibodies. Blood group AB has both A and B antigens, but no antibodies. Blood group B has B antigens with anti-A antibodies in the plasma.
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