APPLIED RADIOLOGICAL ANATOMY

Detailed explanation-1: -This affects motility in the colon, making it difficult to pass stool.

Detailed explanation-2: -Infection. One of the most common causes of megacolon is infection. This includes bacterial infections such as Clostridium difficile, Salmonella, Shigella, and Campylobacter, as well as parasitic infections such as Trypanosoma cruzi (commonly known as Chagas disease) and Entamoeba histolytica.

Detailed explanation-3: -A toxic megacolon is rare, but life-threatening. It is a complication of severe colon disease or infection. Toxic megacolon can be deadly because it puts you at risk for infection throughout the body, shock, and dehydration. Toxic megacolon is a life-threatening condition that needs immediate treatment.

Detailed explanation-4: -Toxic megacolon occurs when swelling and inflammation spread into the deeper layers of your colon. As a result, the colon stops working and widens. In severe cases, the colon may rupture.

Detailed explanation-5: -The condition is present at birth (congenital) as a result of missing nerve cells in the muscles of the baby’s colon. Without these nerve cells stimulating gut muscles to help move contents through the colon, the contents can back up and cause blockages in the bowel.