ANATOMY
GASTRO INTESTINAL
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Clinical experiment is conducted in which one group of subjects is given 50g of glucose intravenously and another group is given 50 g of glucose orally. Which of the following factors can explain why the oral glucose load is cleared from the blood at a faster rate compared to the intravenous glucose load?
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CCK-induced insulin release
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CCK-induced VIP release
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GIP-induced glucagon release
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GIP-induced insulin release
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Explanation:
Detailed explanation-1: -During a swallow, the orad portion of the stomach and lower esophageal sphincter relax at about the same time. Intraluminal pressures in both regions decrease before the arrival of the swallowed bolus. This phenomenon is called receptive relaxation.
Detailed explanation-2: -The presence of fat, such as oleate, in the meal results in stimulation of cholecystokinin (CCK) secretion in the duodenum; in turn, this inhibits antral motility, stimulates pyloric tone and delays gastric emptying [8]. CCK is the first of a repertoire of hormones that regulate gastric emptying.
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