APPLIED RADIOLOGICAL ANATOMY

Detailed explanation-1: -Cholecystokinin (CCK) and gastrin together constitute a family of homologous peptide hormones, which are both physiological ligands for the gastrin/CCK-B receptor, whereas the CCK-A receptor binds only sulfated CCK-peptides. CCK peptides are mainly produced in small intestinal endocrine I-cells and in cerebral neurons.

Detailed explanation-2: -The gastrin family (also known as the gastrin/cholecystokinin family) of proteins is defined by the peptide hormones gastrin and cholecystokinin. Gastrin and cholecystokinin (CCK) are structurally and functionally related peptide hormones that serve as regulators of various digestive processes and feeding behaviors.

Detailed explanation-3: -Cholecystokinin (CCK) is a peptide hormone linked to the gastrointestinal (GI) system. The receptors are expressed in the central nervous system[1] specifically in the hippocampus, cerebral cortex, and striatum [2].

Detailed explanation-4: -Gastrin hormone is secreted in the stomach that stimulates the release of hydrochloric acid in the stomach. Secretin and cholecystokinin are secreted in the duodenum that helps in the production of alkaline bicarbonate in pancreatic juice that neutralizes the acidic contents that enter from the stomach in the duodenum.