APPLIED RADIOLOGICAL ANATOMY

Detailed explanation-1: -Biologically active forms of gastrin Two major forms of gastrin exist, gastrin-34 (G34, composed of 34 amino acids) and gastrin-17 (G17, composed of 17 amino acids). In humans, over 90% of the gastrin present in the antral mucosa is the G17 form.

Detailed explanation-2: -Big gastrin (G34) is one form of gastrin predominate in circulation after a meal, another major form is called little gastrin (G17). Both forms of gastrin have been isolated from human gastrinoma and hog antral mucosa. G34 is carboxy-amidated and can be sulphated or unsulphated at the tyrosine residues.

Detailed explanation-3: -Gastrin is a 101 amino acid peptide that stimulates gastric acid secretion and also acts as a mitogenic factor for gut epithelial cells.

Detailed explanation-4: -Gastrin is a peptide hormone primarily responsible for enhancing gastric mucosal growth, gastric motility, and secretion of hydrochloric acid (HCl) into the stomach. It is present in G cells of the gastric antrum and duodenum.