APPLIED RADIOLOGICAL ANATOMY

Detailed explanation-1: -Gastric mucus is a gel-mucous barrier secreted by epithelial cells and glandular cells in the stomach wall. It acts as part of a barrier that protects the stomach wall from the acid and digestive enzymes within the stomach lumen.

Detailed explanation-2: -THE STOMACH does not digest itself because it is lined with epithial cells, which produce mucus. This forms a barrier between the lining of the stomach and the contents. Enzymes, which make up part of the digestive juices are also secreted by the stomach wall, from glands with no mucus barrier.

Detailed explanation-3: -In the stomach several mucosal defence mechanisms protect the stomach against hydrochloric acid and noxious agents. The pre-epithelial protection is made up by the mucus-bicarbonate barrier. Mucus and bicarbonate, secreted by mucus cells, create a pH gradient maintaining the epithelial cell surface at near neutral pH.

Detailed explanation-4: -Like the colon, the stomach has a two-layered mucus system. The inner mucus layer, built around MUC5AC, acts as a diffusion barrier for hydrochloric acid. The surface epithelial cells secrete bicarbonate, creating a pH gradient from the acidic lumen to neutral pH at the cell surface.

Detailed explanation-5: -The stomach normally does not digest itself because of a mechanism which regulates gastric secretion. This checks the secretion of gastric juice before the content becomes sufficiently corrosive to damage the mucosa. Pure gastric juice can destroy the mucosa and produce a peptic ulcer.