APPLIED RADIOLOGICAL ANATOMY

Detailed explanation-1: -As the surrounding cells are infected and killed by the released viruses, a clear spot on the agar—in the bacterial lawn–develops, called a plaque. The plaques can be counted and the number of virus particles or virions in the original specimen, can be quantified as viruses/ ml or plaque-forming units/ml (PFUs).

Detailed explanation-2: -Plaques are spatially constrained populations of bacteriophages that become visible to the eye as they locally deplete numbers of susceptible bacterial hosts. Plaques develop within what are known as “lawns” of bacteria, as grown either on or in solid or semi-solid media, media which typically is agar-based.

Detailed explanation-3: -This clear spot in the bacterial lawn is called a plaque. Each plaque starts from one phage infecting one cell, so if you count the number of plaques on your plate, you’ll know how many individual bacteriophage particles (or virions) you initially put onto the plate.

Detailed explanation-4: -Plaques form when bacteria are immobilized in a lawn of top agar while phages can slowly diffuse, leading to the formation of a plaque from a single phage-infected cell.

Detailed explanation-5: -Simple Difference: Colony refers to a cluster of particular bacteria developed in a medium. Plaque refers to a clear zone, produced by a Phage which is formed by lysis of the bacterial cells in the medium.