ANATOMY
LYMPHATIC SYSTEM
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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1
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2
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Either A or B
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None of the above
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Detailed explanation-1: -CD4 and CD8 were known as markers for different functional sets of T cells for some time before it became clear that they play an important part in the direct recognition of MHC class II and MHC class I molecules, respectively. CD4 binds to the MHC class II molecule and CD8 to the MHC class I molecule.
Detailed explanation-2: -MHC Class II molecules are a class of major histocompatibility complex (MHC) molecules normally found only on professional antigen-presenting cells such as dendritic cells, mononuclear phagocytes, some endothelial cells, thymic epithelial cells, and B cells. These cells are important in initiating immune responses.
Detailed explanation-3: -Major histocompatibility complex class II molecules (MHC II) are expressed by immune cells like B cells, dendritic cells (DCs), and monocytes/macrophages and designed to stably bind and present fragments from exogenous proteins to the immune system.