APPLIED RADIOLOGICAL ANATOMY

Detailed explanation-1: -Complement fixation systems take advantage of the fact that complement proteins bind, or “fix, ‘’ to antigen-antibody complexes during the host immune response to a foreign antigen. If this antigen is cell localized, then the deposition of complement elements will cause cell lysis.

Detailed explanation-2: -Lysis of the indicator sheep red blood cells signifies both a lack of antibody in patient serum and a negative complement fixation test. If the patient’s serum does contain a complement-fixing antibody, a positive result will be indicated by the lack of red blood cell lysis.