ANATOMY
LYMPHATIC SYSTEM
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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inflammation that occurs throughout the whole body due to a ruptured appendix
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inflammation of the throat due to strep
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inflammation of the lymph vessels
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affects the body’s ability to metabolize fat within cells
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removal of the tonsils
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Detailed explanation-1: -Niemann-Pick is a rare, inherited disease that affects the body’s ability to metabolize fat (cholesterol and lipids) within cells. These cells malfunction and, over time, die. Niemann-Pick disease can affect the brain, nerves, liver, spleen, bone marrow and, in severe cases, lungs.
Detailed explanation-2: -Niemann-Pick disease is a rare genetic condition that affects many of the body’s organs and systems, including the central nervous system. It is one of about 50 diseases classified as lysosomal storage disorders (LSD), where a genetic variation disrupts the normal activity of lysosomes in human cells.
Detailed explanation-3: -Activation of protein kinase C (PKC) has previously been shown to ameliorate the cholesterol transport defect in Niemann Pick Type C1 (NPC1) cells, presumably by increasing the soluble levels of one of its substrates, vimentin.