APPLIED RADIOLOGICAL ANATOMY

Detailed explanation-1: -T cells migrate to the thymus gland, where they become immunocompetent.

Detailed explanation-2: -Most steps in T-cell differentiation occur in the cortex of the thymus. The thymic medulla contains mainly mature T cells.

Detailed explanation-3: -The thymus is the primary site of T cell development, where progenitors from the bone marrow lacking CD4+ and CD8+ coreceptor expression undergo T cell receptor (TCR) rearrangement to generate CD4+CD8+ double positive (DP) thymocytes.

Detailed explanation-4: -The thymus gland is an important part of your immune system. It helps train the white blood cells that protect your immune system. Fortunately, most of your T-cells were produced before you were even born, and the rest were made during childhood and throughout puberty.