ANATOMY
LYMPHATIC SYSTEM
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Which of the following antibodies is almost always found on the surface of B cells and is involved in activation of these B cells?
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IgM
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IgA
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IgD
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IgG
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IgE
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Explanation:
Detailed explanation-1: -IgM is not only the first class of antibody to appear on the surface of a developing B cell. It is also the major class secreted into the blood in the early stages of a primary antibody response, on first exposure to an antigen.
Detailed explanation-2: -Cell-surface, transmembrane antibodies (IgM or IgG) act as receptors for the specific antigen that will activate that particular B cell.
Detailed explanation-3: -B cells have B cell receptors (BCRs) on their surface, which they use to bind to a specific protein. Once the B cells bind to this protein, called an antigen, they release antibodies that stick to the antigen and prevent it from harming the body.
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