ANATOMY
LYMPHATIC SYSTEM
|
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
|
|
|
IgM
|
|
|
IgA
|
|
|
IgD
|
|
|
IgG
|
|
|
IgE
|
Detailed explanation-1: -Placental transfer of maternal IgG antibodies to the fetus is an important mechanism that provides protection to the infant while his/her humoral response is inefficient. IgG is the only antibody class that significantly crosses the human placenta.
Detailed explanation-2: -The efficiency of transplacental transfer of the different IgG subclasses was determined. Transfer of IgG1 and IgG4 was found to be significantly more efficient than that of IgG3 and IgG2. IgG2 was the subclass least efficiently transferred from mother to fetus.
Detailed explanation-3: -Abstract. THE IgG of the neonatal human infant is almost entirely derived by selective transplacental passage of maternal IgG, but IgA and IgM are considered incapable of transplacental passage.