APPLIED RADIOLOGICAL ANATOMY

ANATOMY

LYMPHATIC SYSTEM

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which of the following is a nonspecific defense cell that produces a toxin (perforin) to kill foreign cells?
A
interferons
B
cytotoxic killer T cells
C
phagocytes
D
natural killer cells
Explanation: 

Detailed explanation-1: -The cytotoxic T cells are capable of recognizing antigens on the surface of infected body cells. The cytotoxic T cells bind to the infected cells and secrete cytotoxins that induce apoptosis (cell suicide) in the infected cell and perforins that cause perforations in the infected cells.

Detailed explanation-2: -Cytotoxic CD8 T cells carry out their killing function by releasing two types of preformed cytotoxic protein: the granzymes, which seem able to induce apoptosis in any type of target cell, and the pore-forming protein perforin, which punches holes in the target-cell membrane through which the granzymes can enter.

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