APPLIED RADIOLOGICAL ANATOMY

Detailed explanation-1: -The thymus is the organ primarily responsible for the production and maturation of T cells, functioning as the initial site of T cell immune maturation through positive and negative selection processes. T cells are so named as they mature in the thymus and B cells are named thus, as they mature in the bone marrow.

Detailed explanation-2: -Precursors of T cells migrate from the bone marrow and mature in the thymus. This process is similar to that for B cells, including the sequential rearrangement of antigen receptor gene segments.

Detailed explanation-3: -The thymus is a multi-lobed organ composed of cortical and medullary areas surrounded by a capsule. T cell precursors enter the subcapsular cortical areas, where they encounter networks of cortical epithelial calls (the thymic stroma) and undergo a period of proliferation.