APPLIED RADIOLOGICAL ANATOMY

Detailed explanation-1: -Overview. Muscular dystrophy is a group of diseases that cause progressive weakness and loss of muscle mass. In muscular dystrophy, abnormal genes (mutations) interfere with the production of proteins needed to form healthy muscle. There are many kinds of muscular dystrophy.

Detailed explanation-2: -MD is caused by mutations (alterations) in the genes responsible for healthy muscle structure and function. The mutations mean that the cells that should maintain your muscles can no longer fulfil this role, leading to muscle weakness and progressive disability.

Detailed explanation-3: -Many genes help to make the proteins that protect muscle fibres from damage. Muscular dystrophy occurs if one of these genes does not work properly. Each type of muscular dystrophy is caused by a different change in a gene. Some of these gene changes are inherited from a parent.

Detailed explanation-4: -What causes muscular dystrophy (MD)? Most cases of MD are caused by gene mutations (changes in the DNA sequence) that affect muscle proteins. The mutations are usually inherited, but in some cases they occur spontaneously. These spontaneous mutations can then be inherited by an affected person’s offspring.