APPLIED RADIOLOGICAL ANATOMY

ANATOMY

MUSCULOSKELETAL AND SOFT TISSUE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
The role of osteoclasts is ____
A
To build new bone tissue
B
To help attach ligaments
C
To increase calcium stores in the bone
D
To break old bone tissue down
Explanation: 

Detailed explanation-1: -Osteoclasts dissolve and break down old or damaged bone cells. They make space for osteoblasts to create new bone tissue in areas that are growing or need repair. If osteoblasts are builders, osteoclasts are your bones’ demolition crew. Think clasts for cleaners and blasts for builders.

Detailed explanation-2: -Osteoclasts are the cells that degrade bone to initiate normal bone remodeling and mediate bone loss in pathologic conditions by increasing their resorptive activity.

Detailed explanation-3: -When bone fracture occurs, both osteoblasts and osteoclasts are activated, and they play irreplaceable roles in the healing process of the fracture (5, 6). Soon after fracture, osteoclasts move in to reabsorb dead bone ends, making space for new bone formation (7, 8).

Detailed explanation-4: -OSTEOCLASTS are large cells that dissolve the bone. They come from the bone marrow and are related to white blood cells. They are formed from two or more cells that fuse together, so the osteoclasts usually have more than one nucleus. They are found on the surface of the bone mineral next to the dissolving bone.

Detailed explanation-5: -The osteoclasts remove bone by dissolving the mineral and breaking down the matrix in a process that is called bone resorption. The osteoclasts come from the same precursor cells in the bone marrow that produce white blood cells.

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