APPLIED RADIOLOGICAL ANATOMY

Detailed explanation-1: -There are four major processes: transduction, transmission, modulation, and perception. Transduction refers to the processes by which tissue-damaging stimuli activate nerve endings.

Detailed explanation-2: -Nociceptive pain occurs in 5 phases: 1) Transduction, 2) Conduction, 3) Transmission, 4) Modulation, 5) Perception.

Detailed explanation-3: -There are generally three main stages in the perception of pain. The first stage is pain sensitivity, followed by the second stage where the signals are transmitted from the periphery to the dorsal horn (DH), which is located in the spinal cord via the peripheral nervous system (PNS).

Detailed explanation-4: -Chronic pain is pain that is ongoing and usually lasts longer than six months. This type of pain can continue even after the injury or illness that caused it has healed or gone away. Pain signals remain active in the nervous system for weeks, months or years.