BANKING AFFAIRS

Detailed explanation-1: -Naturally occurring. Anti-A is found in the serum of people with blood groups O and B. Anti-B is found in the serum of people with blood groups O and A. Anti-A and anti-B bind to RBCs and activate the complement cascade, which lyses the RBCs while they are still in the circulation (intravascular hemolysis).

Detailed explanation-2: -ABO antibodies The ‘naturally occurring’ antibodies of the majority of group A or B individuals are mainly IgM and produced in response to environmental ABO antigens, e.g. from microbes in the gut and respiratory tract.

Detailed explanation-3: -The liquid part of your blood without cells (serum) is mixed with blood that is known to be type A and type B. People with type A blood have anti-B antibodies. People with type B blood have anti-A antibodies. Type O blood contains both types of antibodies.

Detailed explanation-4: -A person with Type B blood will have anti-A antibodies in his or her plasma. If the plasma is mixed with Type A blood, the cells will agglutinate, or clump together, from the reaction of the Type A antigens and the anti-A antibodies.