BOTANY
BIOTECHNOLOGY
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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What is a requirement for the production of penicillin in a fermenter?
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adding bubbles of nitrogen gas to mix the nutrients and Penicillium
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adding the required amount of sugar as a nutrient
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ensuring no oxygen enters the fermenter so only anaerobic respiration occurs
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maintaining a constant temperature of 95
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Explanation:
Detailed explanation-1: -Present-day penicillin fermentations are highly automated and computerized. All the necessary precursors, ammonia, sugar, carbon dioxide, oxygen are controlled, with thorough monitoring of temperature and pH for optimal antibiotic production. The pH should be between 6.4 and 6.8 during the active production phase.
Detailed explanation-2: -Penicillium chrysogenum utilizes phenylacetic acid as a side chain precursor in penicillin G biosynthesis. During industrial production of penicillin G, phenylacetic acid is fed in small amounts to the medium to avoid toxic side effects.
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