CHILD DEVELOPMENT PEDAGOGY

Detailed explanation-1: -In prophase, the replicated chromosomes pairs get compact and condense; these paired chromosomes are considered as sister chromatids that attach together by centromeres. Spindle fibers made of microtubule proteins start to appear in this stage that are found in both poles of the cell.

Detailed explanation-2: -The spindle fibers form during prophase. During metaphase of cell division, the spindle fibers radiate from the centrioles at the opposite poles. Some of them attach to the kinetochores of the chromosomes while others bind to the arms of the chromosomes, still others continue to grow.

Detailed explanation-3: -During prophase, the complex of DNA and proteins contained in the nucleus, known as chromatin, condenses. The chromatin coils and becomes increasingly compact, resulting in the formation of visible chromosomes.

Detailed explanation-4: -Explanation: The mitosis (M) phase of the cell cycle has four sequential stages: prophase, metaphase, anaphase, and telophase. In the first stage, prophase, each chromosome becomes condensed and more visible, and there is the breakdown of the nuclear membrane and appearance of spindle fibers.

Detailed explanation-5: -The mitotic spindle also begins to develop during prophase. As the cell’s two centrosomes move toward opposite poles, microtubules gradually assemble between them, forming the network that will later pull the duplicated chromosomes apart.