CHILD DEVELOPMENT PEDAGOGY

Detailed explanation-1: -The first and longest phase of mitosis is prophase. During prophase, chromatin condenses into chromosomes, and the nuclear envelope (the membrane surrounding the nucleus) breaks down. In animal cells, the centrioles near the nucleus begin to separate and move to opposite poles of the cell.

Detailed explanation-2: -During prophase, the nucleus disappears, spindle fibers form, and DNA condenses into chromosomes (sister chromatids).

Detailed explanation-3: -During prophase, the chromosomes condense, the nucleolus disappears, and the nuclear envelope breaks down.

Detailed explanation-4: -During metaphase, the nuclear membrane disappears and the chromosomes become aligned half way between the centrioles. The centromere of each doubled chromosome becomes attached by thread-like spindle fibers to the centrioles which are at polar opposite sides of the cell.

Detailed explanation-5: -Anaphase begins when the cohesion proteins located between the sister chromatids disappear; the sister chromatids, located at the equator of the metaphase plate, separate and begin their migration toward the opposite poles of the mitotic spindle.