GROWTH DEVELOPMENT CHILD
GROWTH AND DEVELOPMENT
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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G1 checkpoint
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G2 checkpoint
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M checkpoint
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G0 checkpoint
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Detailed explanation-1: -The G2/M checkpoint is controlled by Cdc2/cyclinB, and their negative regulators including p21Cip1 and p27 [9]. Weakened G2/M checkpoint under therapeutic setting may trigger cell death via mitotic catastrophe for cells with unrepairable DNA lesions and mitosis machinery.
Detailed explanation-2: -The cell will only pass the checkpoint if it is an appropriate size and has adequate energy reserves. At this point, the cell also checks for DNA damage. A cell that does not meet all the requirements will not progress to the S phase.
Detailed explanation-3: -At the G2 checkpoint, the cell checks for: DNA damage. DNA replication completeness.
Detailed explanation-4: -During the second gap phase, or G 2start subscript, 2, end subscript phase, the cell grows more, makes proteins and organelles, and begins to reorganize its contents in preparation for mitosis.