2016
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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CRIMSR-Cas0
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CRISPR-Cas9
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SERFM-Gas6
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NHTRES-Cas3
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Detailed explanation-1: -The origin of genome editing technology began with the introduction of zinc finger nucleases (ZFNs). Zinc finger nucleases are artificially engineered restriction enzymes for custom site-specific genome editing. Zinc fingers themselves are transcription factors, where each finger recognizes 3–4 bases.
Detailed explanation-2: -Here, we review recent advances of the three major genome editing technologies (ZFNs, TALENs, and CRISPR/Cas9) and discuss the applications of their derivative reagents as gene editing tools in various human diseases and potential future therapies, focusing on eukaryotic cells and animal models.
Detailed explanation-3: -The first such system to be developed for use in genome editing of human cells, known as CRISPR/Cas9, is based on RNA-guided targeting and is much simpler, faster, and cheaper than earlier methods.