CURRENT AFFAIRS

Detailed explanation-1: -DNA origami in the shape of the Mona Lisa, and with the potential to treat cancer.

Detailed explanation-2: -DNA origami has been used for construction of nanorobots and other structures for studies of fluorescence, enzyme-substrate interactions, molecular motor actions, various light and other energy studies, and for drug delivery.

Detailed explanation-3: -DNA origami has its roots in the discovery of the Holliday junction, a temporary branched nanostructure formed during meiosis. Nadrian Seeman pioneered DNA nanotechnology by using immobile Holliday junctions along with sticky ends and double-crossover motifs to create elementary structures.

Detailed explanation-4: -The idea of using DNA as a construction material was first introduced in the early 1980s by Nadrian Seeman. The current method of DNA origami was developed by Paul Rothemund at the California Institute of Technology.

Detailed explanation-5: -DNA origami is created via self-assembly. The combination of heat and chemical denaturation of double-stranded DNA scaffold strands in the presence of staple strands, followed by a sudden drop in temperature and stepwise dialysis to remove chemical denaturant favors self-assembly.