CURRENT AFFAIRS

Detailed explanation-1: -Severe Combined Immunodeficiency (SCID)

Detailed explanation-2: -ADA-SCID. The first primary immune deficiency to be treated with gene therapy was the adenosine deaminase-severe combined immuno deficiency (ADA-SCID).

Detailed explanation-3: -SCID Gene Therapy. Severe Combined Immunodeficiency Disease (SCID) is due to a defective gene for Adenosine Deaminase (ADA). A retrovirus, which is capable of transferring it’s DNA into normal eukaryotic cells (transfection), is engineered to contain the normal human ADA gene.

Detailed explanation-4: -Combined immunodeficiency - also called combined immune deficiency or CID - is a genetic condition of the immune system. It’s known as a “primary immunodeficiency.” Children inherit the gene for CID from their parents. CID occurs when gene mutations cause defects in the immune system.