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Detailed explanation-1: -This result confirmed the first human infection case with BV in China. Identification of the first human infection case with monkey B virus by rtPCR.

Detailed explanation-2: -As noted, B virus was initially isolated from rabbit brain homogenates following fatal zoonotic infections. Within a decade after its discovery, chorioallantoic membranes or embryonated eggs were used for growth and propagation of B virus.

Detailed explanation-3: -Notes from the Field: First Human Infection Case of Monkey B Virus Identified in China, 2021. Monkey B virus (BV), initially isolated in 1932, is currently designated as Macacine alphaherpesvirus 1 by the International Committee on Taxonomy of Viruses (1).

Detailed explanation-4: -B virus infection is extremely rare, but it can lead to severe brain damage or death if you do not get treatment immediately. People typically get infected with B virus if they are bitten or scratched by an infected macaque monkey, or have contact with the monkey’s eyes, nose, or mouth.

Detailed explanation-5: -Since B virus was identified in 1932, only 50 people have been documented to have infections; 21 of them died. Most of these people got infected after they were bitten or scratched by a monkey, or when tissue or fluids from a monkey got on their broken skin, such as by needle stick or cut.