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Detailed explanation-1: -Four private citizens made history Friday by launching into orbit on the first wholly private mission to the International Space Station with an all-civilian crew.

Detailed explanation-2: -Inspiration 4 was the first all civilian orbital spaceflight mission and the first human orbital spaceflight not funded by a nation state. They also made the highest human orbit of the 21st century.

Detailed explanation-3: -Isaacman, who commanded the mission, donated the remaining three seats of his four-person flight to sponsor St. Jude. The first crewmember to join him was Hayley Arceneaux, 29, a physician assistant at St. Jude in Memphis who, as a child, also received treatment for bone cancer from the same organization.

Detailed explanation-4: -SpaceX just launched civilians to the International Space Station. Here’s what you need to know.

Detailed explanation-5: -The four crew members - astronauts Nicole Mann and Josh Cassada of NASA, astronaut Koichi Wakata of JAXA, or Japan Aerospace Exploration Agency, and cosmonaut Anna Kikina of Roscosmos - took off aboard a SpaceX Crew Dragon spacecraft at 12 p.m. ET from Kennedy Space Center in Florida.