EVERYDAY SCIENCE

Detailed explanation-1: -Immunization: A process by which a person becomes protected against a disease through vaccination. This term is often used interchangeably with vaccination or inoculation.

Detailed explanation-2: -Smallpox vaccination provides full immunity for 3 to 5 years and decreasing immunity thereafter. If a person is vaccinated again later, immunity lasts even longer. Historically, the vaccine has been effective in preventing smallpox infection in 95% of those vaccinated.

Detailed explanation-3: -ACAM2000. ® The U.S. Food and Drug Administration (FDA) has licensed ACAM2000®, (Smallpox [Vaccinia] Vaccine, Live), a replication-competent vaccine, for active immunization against smallpox disease in persons determined to be at high risk for smallpox infection.

Detailed explanation-4: -It begins releasing antibodies to fight the germ-think of antibodies as soldiers designed to fight off the specific germ you have. This process can take a few days. The antibodies work to attack, weaken, and destroy the germ. Afterwards, your immune system remembers the germ.

Detailed explanation-5: -Vaccination became widely accepted and gradually replaced the practice of variolation. At some point in the 1800s, the virus used to make the smallpox vaccine changed from cowpox to vaccinia virus.