EVERYDAY SCIENCE

Detailed explanation-1: -Isoenzymes. Isoenzymes (also called isozymes) are alternative forms of the same enzyme activity that exist in different proportions in different tissues. Isoenzymes differ in amino acid composition and sequence and multimeric quaternary structure; mostly, but not always, they have similar (conserved) structures.

Detailed explanation-2: -Isozymes allows differential regulation, such as tissue expression pattern, subcellular localization, and post-translational modifications, thus enabling new biological functions(2–4). However, in many cases, the functional difference of isozymes is not very well understood.

Detailed explanation-3: -Strictly speaking, enzymes with different amino acid sequences that catalyse the same reaction are isozymes if encoded by different genes, or allozymes if encoded by different alleles of the same gene; the two terms are often used interchangeably.

Detailed explanation-4: -Differences of Isozymes and Enzymes An enzyme known as an allozyme can be produced in several forms by a single gene. An enzyme known as an isozyme, on the other hand, is produced in many forms by various genes. This is the primary distinction between isozymes and allozymes.

Detailed explanation-5: -LDH-1: found in heart and red blood cells. LDH-2: found in white blood cells. LDH-3: found in lung tissue. LDH-4: found in white blood cells, kidney and pancreas cells, and lymph nodes. LDH-5: found in the liver and muscles of skeleton. 07-Dec-2020