EVERYDAY SCIENCE

Detailed explanation-1: -Polymerase is found in a complex with primase, and it appears to function in conjunction with primase to synthesize short RNA-DNA fragments during lagging strand synthesis.

Detailed explanation-2: -Primase is an enzyme that synthesizes short RNA sequences called primers. These primers serve as a starting point for DNA synthesis. Since primase produces RNA molecules, the enzyme is a type of RNA polymerase.

Detailed explanation-3: -The order of enzymes in DNA replication include the following: DNA helicase, RNA primase, DNA polymerase, and finally DNA ligase. During the process of DNA replication, the double helix unwinds with the help of the enzyme DNA helicase.

Detailed explanation-4: -Primase is the enzyme that synthesizes RNA primers, oligonucleotides that are complementarily bound to a nucleic acid polymer. Primase is required because DNA polymerases cannot initiate polymer synthesis on single-stranded DNA templates; they can only elongate from the 3′-hydroxyl of a primer.

Detailed explanation-5: -RNA primers for DNA replication are usually synthesized by specialized enzymes, the primases. However, some replication systems have evolved to use cellular DNA-dependent RNA polymerase for primer synthesis.