EVERYDAY SCIENCE

SCIENCE

CELL BIOLOGY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Basic Nucleosome model make DNA fibril of about
A
10 nm
B
30nm
C
100nm
D
300 nm
Explanation: 

Detailed explanation-1: -A zig-zag array of the nucleosomes, in which DNA is wrapped around spaced core histone octamers, is referred to throughout as the 10-nm chromatin fiber (Figure 1, bottom center) [1, 2]. An interphase chromosome at its core is a single very long 10-nm chromatin fiber that is highly organized in the nucleus.

Detailed explanation-2: -DNA is wrapped around core histones, forming a nucleosome fiber (10-nm fiber). This fiber has long been assumed to fold into a 30-nm chromatin fiber and subsequently into helically folded larger fibers or radial loops.

Detailed explanation-3: -Properties of the 30-nm fibre It consists of a helical array of nucleosomes, each comprising a core particle wrapping ∼146 or 147 base pairs (bp) of DNA associated with a linker histone.

Detailed explanation-4: -Nucleosomes are the basic units of DNA packaging in eukaryotes. They contain   147 bp of DNA, wrapped around a histone octamer, in about 1.7 superhelical turns [1, 2, 3].

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