EVERYDAY SCIENCE

Detailed explanation-1: -Paul Boyer, a UCLA Professor, developed the binding change, or flip-flop, mechanism theory, which postulated that ATP synthesis is dependent on a conformational change in ATP synthase generated by rotation of the gamma subunit.

Detailed explanation-2: -The conformational hypothesis of Paul Boyer implied an enzyme where ATP synthesis was driven by the energy of conformational changes in the respiratory proteins. This was finally abandoned as an explanation of the overall process.

Detailed explanation-3: -(2) Conformational coupling hypothesis: It was formed by “Poul boyer”. According to this hypothesis, electron transport cause4s activation of proteins of inner mitochondrial membrane. These activated proteins in some way associated with ‘ATP synthase’.

Detailed explanation-4: -In 1974 Paul Boyer presented a theory explaining how ATP synthase works. The theory was substantiated in 1994 when John Walker used X-ray crystallography to determine the structure of ATP synthase.