EVERYDAY SCIENCE

Detailed explanation-1: -The most basic difference between RER and SER is the presence of ribosomes. When ribosomes attach to the surface of an ER, it gives a characteristic rough appearance; hence it is called Rough ER. On the other hand, a smooth ER does not have ribosomes on its surface. It possesses ribosomes attached to its membrane.

Detailed explanation-2: -The rough ER, studded with millions of membrane bound ribosomes, is involved with the production, folding, quality control and despatch of some proteins. Smooth ER is largely associated with lipid (fat) manufacture and metabolism and steroid production hormone production. It also has a detoxification function.

Detailed explanation-3: -The rough endoplasmic reticulum contains ribosomes and makes protein, whereas the smooth endoplasmic reticulum does not contain ribosomes and functions to make lipids and detoxify the cell. Large amounts of smooth ER are found in cells that participate in lipid metabolism and detoxify the body, such as liver cells.

Detailed explanation-4: -The ER can be classified in two functionally distinct forms: smooth endoplasmic reticulum (SER) and rough endoplasmic reticulum (RER). The morphological distinction between the two is the presence of protein-synthesizing particles, called ribosomes, attached to the outer surface of the RER.