EVERYDAY SCIENCE

Detailed explanation-1: -Palade realized that the dots on the surface of the rough ER were ribosomes synthesizing secretory proteins. This was not only the first function assigned to the ER but also a revolutionary idea: Secretory proteins would cross an intracellular membrane, rather than the plasma membrane.

Detailed explanation-2: -Ribosomes: these small dot-like structures contain protein and ribosomal RNA.

Detailed explanation-3: -The ribosomes attached to the ER are being used to make proteins that are inserted into the membrane, proteins that are to be secreted out of the cell, and proteins that are found in various membrane bound organelles like the Golgi. Ribosomes floating freely synthesize all the other proteins.

Detailed explanation-4: -Ribosomes on the rough endoplasmic reticulum are called ‘membrane bound’ and are responsible for the assembly of many proteins. This process is called translation. Certain cells of the pancreas and digestive tract produce a high volume of protein as enzymes.