EVERYDAY SCIENCE

SCIENCE

CELL BIOLOGY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
NaCl is isotonic to red blood cells. Which of these describes what will happen if a technician misplaces a decimal point and makes 9.0% NaCl solution instead and administers it to a patient?
A
The cells exposed to the solution will burst.
B
The cells exposed to the solution will shrink.
C
The cells will remain the same size.
D
The cells exposed to the solution will expand but not burst.
Explanation: 

Detailed explanation-1: -0.9% NaCl is isotonic to red blood cells. Which of these describes what will happen if a technician misplaces a decimal point and makes 9.0% NaCl solution instead and administers it to a patient? The cells exposed to the solution will burst.

Detailed explanation-2: -Since the concentration of NaCl (solute) is higher than the 0.9%, water flows outwardly from the cell due to exosmosis causing the cell to shrink. Therefore, shrinking of the red blood cell will be seen if placed in a solution containing a 0.99% NaCl concentration.

Detailed explanation-3: -When a red blood cell is placed in an isotonic solution, there will be no net movement of water. Both the concentration of solute and water are equal both intracellularly and extracellularly; therefore, there will be no net movement of water towards the solution or the cell.

Detailed explanation-4: -Washing of erythrocytes with 0.85% solution of NaCl decreased the pH and hemoglobin affinity to oxygen to such an extent that the Bohr effect increased as the result of effect of chloride ions on hemoglobin properties added to the effects of pH.

Detailed explanation-5: -A 0.9% NaCl solution is said to be isotonic: when blood cells reside in such a medium, the intracellular and extracellular fluids are in osmotic equilibrium across the cell membrane, and there is no net influx or efflux of water.

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