EVERYDAY SCIENCE

Detailed explanation-1: -The spindle is a complex microtubule-based superstructure responsible for chromosome movement and segregation during mitosis and meiosis (McIntosh and Koonce 1989; Mitchison 1989a; Rieder 1991; Hyman and Karsenti 1996; Compton 2000).

Detailed explanation-2: -Microtubules form the mitotic apparatus (mitotic spindle) whose main function is to separate chromosomes to the newly dividing cells (Fig. 5).

Detailed explanation-3: -Kinetochore microtubules attach end-on to the kinetochore, which forms at the centromere of each duplicated chromosome. They serve to attach the chromosomes to the spindle. Overlap microtubules interdigitate at the equator of the spindle and are responsible for the symmetrical, bipolar shape of the spindle.

Detailed explanation-4: -Mitotic spindle, present at the poles of the cells, is a structure made of microtubules (spindle fibres). Its role is to separate the chromosomes. The spindle fibres attach to chromosomes during metaphase and pull the chromatids towards opposite poles during anaphase.

Detailed explanation-5: -The spindle apparatus is a structure of the eukaryotic cytoskeleton involved in mitosis and meiosis, often referred to as the mitotic spindle during mitosis and the meiotic spindle during meiosis. Its function is to segregate chromosomes during cell division (either mitosis or meiosis) to the daughter cells.