EVERYDAY SCIENCE

SCIENCE

CELL BIOLOGY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
The Linker histone is ____
A
H1
B
H3
C
H4
D
H2A
Explanation: 

Detailed explanation-1: -The linker histone H1 family members are a key component of chromatin and bind to the nucleosomal core particle around the DNA entry and exit sites. H1 can stabilize both nucleosome structure and higher-order chromatin architecture.

Detailed explanation-2: -Linker histone is mainly a nucleus protein that binds to the linker DNA as well as the nucleosome to enhance the condensation of the chromatin. It exerts its influence on the transcriptional activities of certain genes.

Detailed explanation-3: -Linker histones H1 are ubiquitous chromatin proteins that play important roles in chromatin compaction, transcription regulation, nucleosome spacing and chromosome spacing. H1 function in DNA and chromatin structure stabilization is well studied and established.

Detailed explanation-4: -Histones H2A, H2B, H3, and H4 are known as the core histones, and histones H1 and H5 are known as the linker histones.

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