EVERYDAY SCIENCE

SCIENCE

CELL BIOLOGY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What is the most likely pathway taken by a newly synthesized protein that will be secreted by a cell?
A
ER, golgi, nucleus
B
Golgi, ER, lysosome
C
nucleus, ER, Golgi
D
ER, golgi, vesicles that fuse with plasma membrane
Explanation: 

Detailed explanation-1: -Golgi → Rough ER → Lysosome → Transport vesicle → Cell membrane.

Detailed explanation-2: -Newly synthesized proteins enter the endomembrane system through the endoplasmic reticulum. From there them move through the Golgi apparatus and into either the Secretory Pathway or the Lysosomal Pathway.

Detailed explanation-3: -These experiments defined a pathway taken by secreted proteins, the secretory pathway: rough ER → Golgi → secretory vesicles → cell exterior.

Detailed explanation-4: -ER-to-Golgi transport is the first step in the secretory pathway. At the ER, proteins destined for the extracellular space or to organelles along the route are packaged into vesicles that transport them to the Golgi apparatus.

Detailed explanation-5: -The pathway for protein synthesis is from DNA to mRNA to protein. Protein synthesis has two main steps, transcription and translation. Transcription occurs in the nucleus and copies DNA to mRNA. This is important because mRNA can be processed and exported to the cytoplasm, whereas DNA needs to stay in the nucleus.

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