EVERYDAY SCIENCE

Detailed explanation-1: -Everyone has two copies of the BRCA1 and BRCA2 genes, one copy inherited from their mother and one from their father. Even if a person inherits a BRCA1 or BRCA2 mutation from one parent, they still have the normal copy of the BRCA1 or BRCA2 gene from the other parent.

Detailed explanation-2: -When a mutation damages either of these genes, the person’s risk of cancer increases. Inheriting damaged copies of the BRCA1 or BRCA2 genes can increase the risk for breast cancer and ovarian cancer in women and the risk for breast and prostate cancer in men, as well as other cancers.

Detailed explanation-3: -What are BRCA1 and BRCA2? BRCA1 (BReast CAncer gene 1) and BRCA2 (BReast CAncer gene 2) are genes that produce proteins that help repair damaged DNA. Everyone has two copies of each of these genes-one copy inherited from each parent.

Detailed explanation-4: -What is Cancer Predisposition Syndrome? Cancer predisposition syndrome, also called inherited cancer predisposition, hereditary cancer predisposition, or family cancer predisposition is a genetic mutation that increases the chances of developing cancer at an earlier age compared to the risk for the general population.