EVERYDAY SCIENCE

Detailed explanation-1: -One clear definition is the following: “Selectivity of a method refers to the extent to which it can determine particular analyte(s) in a complex mixture without interference from other components in the mixture” [1].

Detailed explanation-2: -Selectivity is a measure of a method’s freedom from interferences.5 The selectivity of a method for the interferent. relative to the analyte is defined by a selectivity coefficient, KA, I. KA, I = kI / kA which may be positive or negative depending on the sign of kI and kA.

Detailed explanation-3: -Selectivity of a method refers to the extent to which it can. determine particular analyte(s) in a complex mixture. without interference from other components in the mixture. A method which is perfectly selective for an analyte or. group of analytes is said to be specific.

Detailed explanation-4: -Selectivity is the quality of a response that can be achieved without interference for any other substance. Sensitivity is how low can you detect the substance of interest. The best analytical method offers the highest sensitivity and highest selectivity.

Detailed explanation-5: -Selectivity and Specificity [10] The term specificity generally refers to a method that produces a response for a single analyte only, while the term selective refers to a method that provides responses for a number of chemical entities that may or may not be distinguished from each other.