EVERYDAY SCIENCE

Detailed explanation-1: -Finally, a protocol is a set of stringent guidelines that specify a procedure that an analyst must follow if an agency is to accept the results. Protocols are common when the result of an analysis supports or defines public policy.

Detailed explanation-2: -1.3 PARAMETERS FOR METHOD VALIDATION To be fit for the intended purpose, the method must meet certain validation characteristics. Typical validation characteristics, which should be considered are: selectivity (specificity), linearity, range, accuracy, precision, limit of detection and quantitation.

Detailed explanation-3: -Analytical method validation characteristics which should be considered during performing of method validation; Accuracy. Precision. Specificity.

Detailed explanation-4: -Specificity. Specificity is the ability to assess unequivocally the analyte in the presence of components which may be expected to be present. Typically these might include impurities, degradants, matrix, etc.

Detailed explanation-5: -It is important to understand that the term specificity is used to tell something about the method’s ability responding to one single analyte only, while selectivity is used when the method is able to respond to several different analytes in the sample.