EVERYDAY SCIENCE

Detailed explanation-1: -Red blood cells are formed in the red bone marrow of bones. Stem cells in the red bone marrow are called hemocytoblasts. They give rise to all of the formed elements in blood. If a stem cell commits to becoming a cell called a proerythroblast, it will develop into a new red blood cell.

Detailed explanation-2: -Thrombocytes (platelets) Megakaryocytes develop from hemocytoblasts in the red bone marrow. Thrombocytes become sticky and clump together to form platelet plugs that close breaks and tears in blood vessels. They also initiate the formation of blood clots.

Detailed explanation-3: -The hemocytoblast forms two types of descendants-the lymphoid stem cell, which produces lymphocytes, and the myeloid stem cell, which can produce all other classes of formed elements.

Detailed explanation-4: -Hemocytoblasts, or multipotent hematopoietic stem cells, give rise to myeloid stem cells, which differentiate into myeloblasts, megakaryocytes, and red blood cells (erythrocytes). Red blood cell production is regulated by the hormone erythropoietin, which is produced by cells in the kidneys and liver.

Detailed explanation-5: -The standard model of erythropoiesis starts with hematopoietic stem cells (HSCs) in the bone marrow (BM), giving rise to multipotent progenitors that go on to erythroid-committed precursors to mature RBC.