EVERYDAY SCIENCE

Detailed explanation-1: -Thromboplastin converts prothrombin in the plasma to thrombin. Vitamin K and Calcium ions are essential for the synthesis of prothrombin. Thrombin further converts the fibrinogen in the plasma to fibrin. Then, a blood clot is formed by the entangling of platelets and red blood cells in the fibrin network.

Detailed explanation-2: -The proteolytic conversion of prothrombin to thrombin catalysed by prothrombinase is one of the more extensively studied reactions of blood coagulation.

Detailed explanation-3: -Prothrombin is transformed into thrombin by a clotting factor known as factor X or prothrombinase; thrombin then acts to transform fibrinogen, also present in plasma, into fibrin, which, in combination with platelets from the blood, forms a clot (a process called coagulation).

Detailed explanation-4: -Thromboplastin is secreted by the platelets. It is a plasma protein which aids in blood coagulation through catalyzing the conversion of prothrombin to thrombin.

Detailed explanation-5: -The synthesis of thromboplastin, a potent trigger of blood coagulation, can be induced in human peripheral blood monocytes.